Associate Director, Data Architect

Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS). Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems, we encourage you to read the opportunity below and apply. The Opportunity Amylyx Pharmaceuticals is seeking a highly motivated Associate Director, Data Architecture to lead the design, implementation, and evolution of our enterprise data platform as we prepare for commercial growth and future product launches. This individual will play a key role in building a scalable, modern data ecosystem centered on Snowflake, enabling trusted, high-quality data across Commercial, Medical Affairs, Patient Services, Finance, R&D, Quality, and Corporate functions. The role combines enterprise data architecture, solution delivery leadership, and stakeholder engagement. The successful candidate will serve as the technical lead for enterprise data initiatives and will partner closely with business stakeholders, external vendors, managed service providers, and implementation partners to establish a robust and scalable data foundation that supports operational excellence, analytics, reporting, and AI-enabled insights. This is a hands-on leadership role requiring both strategic vision and deep technical expertise across data architecture, integration, data engineering, data governance, and business intelligence. Responsibilities Enterprise Data Architecture Define and maintain Amylyx's enterprise data architecture roadmap and target-state data platform. Lead data architecture and solution design for new business domains including Commercial, Finance, HR, R&D, Quality, and Regulatory. Establish scalable data architecture patterns for ingestion, transformation, storage, governance, reporting, and analytics. Develop and maintain enterprise data models, canonical data structures, and integration standards. Commercial Data Platform & Launch Readiness Lead development and expansion of Amylyx's Commercial Data Hub and enterprise data warehouse. Design and oversee integration of key commercial data sources including: CRM, Specialty Pharmacy, Specialty Distributor, Patient Services, Claims and Prescription Data, Formulary and Market Access Data, Customer Master Data, etc. Support commercial launch planning through delivery of high-quality, trusted data and reporting capabilities. …