Associate Principal Scientist - Formulation and Process Design

About AstraZeneca: AstraZeneca is a global, science-led biopharmaceutical company and our innovative medicines are used by millions of patients worldwide. This is the place to make an impact. Here we ensure everyone can reach their full potential, perform at their best and make a valued contribution to the enterprise! About Pharmaceutical Technology & Development (PT&D) and Global Product Development (GPD): PT&D is the bridge that turns brilliant science into real medicines, spanning the entire value chain—from early toxicology and clinical supplies to technology that enables robust commercial manufacture. Within PT&D, GPD leads the late‑stage design and development of drug products across a range of dosage forms. We develop the formulation, manufacturing process, and scientific understanding needed to scale, launch, and sustain new medicines. You’ll collaborate in highly multidisciplinary teams with engineers and pharmaceutical scientists to advance life-changing medicines for patients. The Opportunity: We are seeking an Associate Principal Scientist within Formulation and Process Design, that can balance formulation development and process engineering with a passion for application of digital tools with experience in solid dosage product development (tablets, capsules). In this role you will work closely with a team of colleagues in a multi-disciplinary environment to assess, design, develop and deliver high quality clinical and commercial formulations and processes.  You can expect to contribute to programs at laboratory scale with line of sight for commercial manufacture by using modelling and simulation approaches as first intent combined with hands-on experimental work as needed. You will play a key role in leading the formulation aspects of projects in late-stage development spanning an exciting portfolio of oral solid dosage forms (including Continuous Direct Compression).  You will be an important member of a multidisciplinary team, providing input to the overall product development, designing and executing lab based and pilot plant work packages and driving the development and implementation of in silico tools to support and accelerate development. You will be a recognized problem solver and team player who thrives under pressure and has a passion for ensuring product robustness through the development of manufacturing processes which are well understood, controlled, and capable of meeting long‑term commercial and patient needs. Key Responsibilities: Lead formulation input for the design and development of robust oral solid dosage forms. Lab-based formulation and process development: plan and execute lab-scale experiments to facilitate project decisions. Shape the scientific and technical direction of product development activities through formulation understanding and process design and control. Help define and optimize critical process parameters (CPPs) and integrate them into control strategies. Lead or contribute…