Scientist, Biochemistry I or II

Scientist, Biochemistry I or II PacBio (NASDAQ: PACB) is a premier life science technology company that designs, develops, and manufactures advanced sequencing solutions to help scientists and clinical researchers resolve genetically complex problems. Our mission is to enable the promise of genomics to better human health. Genomics is core to all biological processes, and our advanced genomics tools provide scientists and clinical researchers the insights to better understand biology and health. We are now entering the century of biology and genomics is at the heart of the next revolution. Become part of the new paradigm in gene sequencing and help shape the future of genomic study by joining the PacBio team. Position Summary: This position will be part of development and manufacturing team to assist commercialization of sequencing platforms. They will be responsible for production of recombinant proteins conforming to product specifications. The ideal candidate would have broad knowledge in protein chemistry/molecular biology, and extensive experience in manufacturing protein products under ISO environment. They will be familiar with analytical tools used for characterization of enzymes, and skilled in troubleshooting and developing corrective solutions. The candidate must have strong collaborative and teamwork attributes Responsibilities: Design and execute studies to develop and improve robustness of protein manufacturing processes Process protein production orders and execute reagent manufacturing activities in a timely manner Maintain records and production environment in compliance with quality standards Conduct troubleshooting on issues which arise during routine production Maintain, qualify, and validate equipment as appropriate Perform quality control tests Assist in inventory management and ordering materials Collaborate cross-functionally to ensure on-time completion of production builds Conduct development and technology transfer of reagent manufacturing processes and documentation Conduct new process development and transfer to production Required Qualifications: A minimum of MSc degree in Biochemistry, Protein Chemistry, Molecular Biology, or related scientific discipline A minimum of 5 years of experience in the Life Sciences industry Experience of minimum of 3 years in recombinant protein production, preferably with DNA polymerases Experience working with affinity chromatography, IEX, HIC, and SEC, preferably for recombinant protein from bacterial expression system Substantial experience with automated chromatography stations such as AKTA systems Experience in analytical methodologies for protein characterization including HPLC, enzyme kinetics, protein quantification, spectrophotometer, SDS-PAGE Experience in formulation and filtration techniques, such as TFF Team player with the ability to take initiative in a fast-paced environment Excellent interpersonal, written, and verbal communication skills …