Principal Scientist, Flow Cytometry

Position Summary: The Principal Scientist will be instrumental in helping Precision achieve its goals of delivering exceptional services to Precision’s diverse, innovative and global biopharmaceutical clients. Working closely with the Senior Vice President, Lab Operations they will help implement the strategic scientific plan to support translational medicine research, primarily, but not solely, in the Immuno-Oncology and autoimmune/inflammatory space. Key components will be focused on, design and development of innovative qualified and validated immunophenotyping (including high content flow cytometry assays up to 31 markers, receptor occupancy assays, tetramer/dextramer assays as well as immunophenotyping flow based assays), and antigen specific (ELISpot/Fluorospot) or other custom cell based assays. The successful candidate will assist and be a resource for senior team members to design experimental plans and timelines, that match client specifications/requirements. They should and be able to communicate the plan and progress to the client, along with executing and reporting the work according to agreed timelines and under the appropriate regulations (GLP, CAP, CLIA etc.). A significant aspect of this job is the training and mentoring of more junior scientists and team members in bioservices both in laboratory techniques and in the analysis and presentation of data. The role will provide technical expertise to the laboratory as needed, as well as the expectation is that a large part of training is provided “hands on”. Essential functions of the job include but are not limited to: Provide mentoring, coaching and training to Flow Laboratory team members, assist in setting priorities for lab work in collaboration with other team leaders Motivate team, share knowledge on FACS, participate in recruitment process and revenue forecasting Design and implement cell-based assays to meet client requirements; may include complex flow immunophenotyping assays, primary cell based assays. Write and implement standard operating procedures (SOPs) to perform assays to meet client requirements and the level of regulatory compliance needed Utilize current SOPs to perform cell assays such as flow immunophenotyping, ELISpot, and other custom cell based assays. Generate technical reports and other communications required to present data to clients Write posters and papers for submission to conference organizers and peer reviewed journals Write reviews and white papers On occasion, review and edit client proposals, contract/proposals as appropriate. Train scientific staff in the review and presentation of data; including client reports, posters and papers for peer reviewed journals Train technical staff how to perform laboratory procedures. Devise and perform validation schema to ensure staff are superbly trained and competent. Maintain and support safe lab practices and environment Track and trend laboratory efficiency and quality …