Senior Accountant

Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH.   Madrigal’s medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed THR-β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c).   Our success is driven by our people. We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration. To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way. We are seeking a Senior Accountant to join our growing Finance & Accounting team. This role supports core accounting operations including general ledger management, financial close, and inventory accounting within a publicly traded pharmaceutical environment. The position will play a key part in the monthly close process, preparation of journal entries and reconciliations, and maintenance of strong internal controls. The ideal candidate is a detail-oriented accounting professional who thrives in a fast-paced environment and is eager to contribute to continuous process improvement. Key Responsibilities: Support inventory accounting in a pharmaceutical manufacturing environment, including preparation of related journal entries and reconciliations Manage assigned accounting areas, including accruals, prepaid expenses, and fixed assets Prepare monthly journal entries and perform account reconciliations in accordance with US GAAP Support monthly, quarterly, and year-end close cycle, including preparation of journal entries, variance analyses, and supporting schedules Understand the underlying account balances to document and explain period-over-period fluctuations and deliver meaningful and accurate monthly financial analyses Assist with preparation of internal and external financial reporting and supporting schedules along with tie-outs of the financial statements Support external audits during quarterly reviews and year-end audit by preparing requested documentation and analyses Identify and support opportunities for process improvements and increased efficiency Review contracts as needed and model the accounting implications of arrangements in Excel Assist with SOX controls documentation, testing, and compliance efforts Review P&L accounts to ensure proper classification Conduct the annual fixed asset observation…