Senior Manager, Analytics

Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS). Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems, we encourage you to read the opportunity below and apply. The Opportunity Reporting to the Senior Director, Insights and Analytics, the Senior Manager, Analytics will serve as the primary point of contact for commercial analytics supporting the business. This highly visible, hands-on role will deliver insights from claims and other secondary data, lead patient services analytics, provide high-level market access analytics, and help translate strategic questions into clear, actionable business recommendations. The successful candidate will combine strong analytical judgment, technical fluency, and business partnership skills. This individual will align leadership KPIs for visualization in automated dashboards, support leadership team discussions with timely ad hoc analyses, and work closely with Data Management, Information Technology, Field Analytics, Market Access Analytics, Marketing, Commercial Operations, Finance, Market Access, and other cross-functional partners to ensure insights are accurate, compliant, scalable, and decision-oriented. Responsibilities Commercial analytics leadership: Serve as the primary analytics partner to the commercial business, shaping analytical priorities, clarifying business questions, and delivering insights that inform strategy and execution. Claims and secondary data analytics: Analyze longitudinal claims and other secondary data sources to assess patient journeys, treatment dynamics, market trends, customer behavior, and business performance. Patient services analytics: Lead analytics for patient services programs, including defining performance measures, monitoring patient access and support pathways, identifying operational opportunities, and communicating actionable insights to stakeholders. Market access analytics: Provide high-level analytics on access, coverage, reimbursement, payer dynamics, and related barriers to support market access and broader commercial decision-making. Leadership dashboards and KPI alignment: Partner with business leaders to define, prioritize, and govern key performance indicators for automated leadership dashboards, ensuring consistent metric definitions and decision-ready visualization. Ad hoc…