Senior Site Reliability Engineer (Systems Engineer III)
Ophelia · United States · On-site
Pay: USD 140,000 – 150,000 a year
Posted Oct 5, 2026
Sign up free: we match you to jobs like this, tailor your application and fill the form. 2 free applications every day.
Are you looking for a role in a company that's solving one of the greatest challenges of our lifetime? Ophelia helps people end their opioid use and restore their quality of life with respect for their time and dignity. Our mission is to make evidence-based treatments for opioid use disorder (OUD) accessible to everyone... and we're looking to bring more people onto our team to help us achieve it.
Ophelia is a venture-backed, healthcare startup that helps individuals with OUD by providing FDA-approved medication and clinical care through a telehealth platform. Our approach is discreet, convenient, and affordable. We've been successfully operating in 16 states for almost six years and we're excited to continue our growth. We are a team of physicians, scientists, entrepreneurs, researchers and White House advisors, backed by leading technology and healthcare investors working to re-imagine and re-build OUD treatment in America.
About the Role
As a Senior Site Reliability Engineer (SE III) at Ophelia, you will be our dedicated reliability, availability, and performance hire, playing a key role in making the systems that support our mission of treating opioid use disorder through telehealth stable, observable, and fast. Our stack is TypeScript on Node, React, and Firebase (e.g., Firestore, Authentication, Hosting) running on Cloud Run in Google Cloud Platform (GCP). Your work will have a direct impact on patients, clinicians, and our ability to scale.
You will own and drive our system stability and availability initiative, which is already underway: Terraform-driven uptime checks feed our engineering key performance indicators (KPIs), we have an initial service level objective (SLO) plan, and we've recently revamped our on-call rotation and runbook to keep the on-call engineer focused on severity incidents (SEVs). You will take this from a good start to a mature practice: defining and operationalizing SLOs, building out logging, monitoring, and alerting grounded in sound measurement (e.g., percentile-based latency indicators rather than averages), moving incident response into PagerDuty with clear categorization and escalation paths, expanding our infrastructure as code (IaC) footprint, and working down known pain points such as long-latency endpoints and Cloud Run cold starts. You will also partner closely with our head of IT on IAM hardening, secrets management, audit logging, and HIPAA/SOC 2 infrastructure controls. You will be the directly responsible individual (DRI) for our mean time to recovery (MTTR) KPI and for the measurement and reporting of our availability KPIs.
As a senior engineer, you will be a force multiplier for our team of fullstack engineers who are focused on product work. That means leveling up the team's GCP and DevOps skills through documentation, runbooks, pairing, and code review, and bringing reliability recommendations to new features as they are designed, while primarily owning the infrastructure work…