Vice President, Program Management

Uniquity Bio is a clinical-stage biotechnology company committed to putting science and patients first. We exist to develop transformative new medicines for immune-mediated diseases, and we’re looking for bright-minded professionals driven by a desire to advance science and make a difference for people in need. Our lead asset, solrikitug, is a highly-potent TSLP inhibitor now in Phase 2 clinical trials for asthma, chronic obstructive pulmonary disease (COPD), and eosinophilic esophagitis (EoE) indications. Join us in building an organization where people and science thrive together. You’ll have the opportunity to make a meaningful impact while working alongside a talented, agile team in an environment where ideas move quickly, colleagues are trusted, and quality remains a cornerstone. Position Overview The Vice President of Program Management drives the strategic and operational execution of the company’s late-stage (Phase 2 and Phase 3) development programs. This position will report to the CEO and is a key member of the leadership team. This individual will drive integrated program strategy, execution and decision making partnering closely with cross-functional leaders to ensure clinical and regulatory success, and deliver critical value inflection points in a lean, fast-paced biotech environment. This role requires a highly experienced, hands-on leader with deep expertise in late-stage clinical development, who can successfully navigate complexity, manage cross functional relationships, and prepare programs for potential registration and commercialization. Key Responsibilities Lead the end-to-end program strategy and execution for Phase 2 and Phase 3 programs. Lead team cross functional team meetings to drive decision making and timelines by synthesizing complexity into clear decision options and plans of action. Contribute to development strategies to support regulatory approval, label optimization, and lifecycle planning. Ensure clear alignment of program goals with corporate objectives, investor expectations, and clinical/regulatory milestones. Oversee integrated program plans supporting global Phase 2b/3 clinical trials, including timelines, budgets, and critical path activities. Partner closely with Clinical Development, Clinical Operations, Biostatistics, Regulatory and CMC to ensure trial execution excellence. Anticipate and proactively mitigate risks related to enrollment, endpoints, regulatory expectations, and data integrity. Prepare and deliver communications for Board meetings highlighting key risks, risk mitigation strategies, and progress against timelines and deliverables. Collaborate with Regulatory Affairs to prepare for key interactions (e.g., End-of-Phase 2, pre-BLA/NDA meetings, and global regulatory submissions). Support development of target product profiles and differentiation strategies in competitive immunology markets. Ensure programs are aligned with future commercialization…